GPC2-CAR T cells tuned for low antigen density mediate potent
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Descrição
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
Mechanisms and strategies for safe chimeric antigen receptor T‐cell activity control - Stock - 2023 - International Journal of Cancer - Wiley Online Library
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice - ScienceDirect
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting
Membrane Proteome Array (MPA), Antibody Specificity Profiling
JCM, Free Full-Text
Full article: B7-H3-targeted CAR-T cell therapy for solid tumors
D3-GPC2-PBD is potently cytotoxic to GPC2-expressing SCLCs (A)
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
Present Status and Advances in Chimeric Antigen Receptor T Cell Therapy for Glioblastoma
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research
Adoptive cell therapy in paediatric extracranial solid tumours: current approaches and future challenges - ScienceDirect
Mechanisms and strategies for safe chimeric antigen receptor T‐cell activity control - Stock - 2023 - International Journal of Cancer - Wiley Online Library
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research
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