Descrição
The drug candidate faces numerous efficacy and safety hurdles before moving forward to clinical testing. Here at the UPDDI we recognize the need for early identification of potential human toxicity and pharmacokinetic issues by creating a unique human liver microphysiological systems platform for drug testing before implementing preclinical animal testing.
Why 90% of clinical drug development fails and how to improve it
Preclinical Studies
Target safety assessments – identifying risk early
Compound Interest: Understanding the Drug Discovery Process
PDF) Molecular clinical safety intelligence: a system for bridging
Pathology in Nonclinical Drug Safety Assessment - ScienceDirect
In vitro safety pharmacology profiling - European Pharmaceutical
Drug discovery and development
Target Profiling
Preclinical safety evaluation of biotechnology-derived
How drugs are discovered and developed - The Physiological Society
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